Retatrutide (GLP-3) 20mg

Retatrutide (GLP‑3) – 20mg

Research Grade | Lyophilized

PeptideFor Laboratory Research Use Only. Not for Human or Veterinary Use.

Retatrutide, also known as a GLP‑3 triple agonist, is a synthetic peptide designed to interact with GLP‑1, GIP, and glucagon receptors. Its multi-receptor activity makes it an advanced tool for metabolic, endocrinology, and cellular signaling research.

This product is supplied as a high-purity, lyophilized peptide powder suitable for in‑vitro and preclinical laboratory applications.

Chemical Information

Compound Name: Retatrutide Synonyms: LY‑3437943, GLP3‑R peptide

Peptide Class: Synthetic multi-receptor agonist peptide

• Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈

• Molecular Weight: ~4,731.3 g/mol

• CAS Number: 2381089‑83‑2

• Purity: ≥99% (HPLC / MS verified)

• Appearance: White to off-white lyophilized powder

• Solubility: Soluble in Bacteriostatic Water, DMSO and aqueous laboratory buffers

• Fill Size: 20 mg per sterile vial

Mechanism & Research Context

Retatrutide acts as a triple receptor agonist:

• GLP‑1 receptor — regulates insulin secretion and appetite signaling

• GIP receptor — modulates insulin sensitivity and metabolic pathways

• Glucagon receptor — influences energy expenditure and cellular metabolism

Its triple-agonist profile makes it distinct from single- or dual-agonist peptides, enabling advanced metabolic and endocrinology research applications.

Potential Research Applications

• In-vitro and ex-vivo incretin system studies

• Glucose regulation and insulin secretion research

• Cellular metabolism and mitochondrial function assays

• Preclinical models of obesity, diabetes, and metabolic disorders

• Multi-pathway hormone signaling studies